AP Wire
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New research shows a novel pill is helping people with advanced pancreatic cancer live longer. It's not a cure, as the drug's effects eventually waned. But it's a very different kind of treatment than the chemotherapy that is a mainstay for these patients. Called daraxonrasib, the drug is designed to block a mutated protein that fuels most cases of pancreatic cancer, one of the deadliest types of cancer. The research was published Sunday in the New England Journal of Medicine and presented at an American Society of Oncology meeting. Maker Revolution Medicines will seek Food and Drug Administration approval.

Governments around the world are being pressed to find and support alternatives to reduce dependency on chemical fertilizers as the Iran war drives up prices. The Gulf region produces 30% of globally traded chemical fertilizer. That’s caused concerns about food supply. Experts say the shift away from chemical fertilizer could benefit the environment since its production and use cause significant global greenhouse gas emissions, the main driver of climate change. In Senegal, farmer Abou Sow has turned to organic compost. In Brazil and India, farmers are exploring biofertilizers and natural farming. But there are challenges including in scaling up availability.

California voters face a crowded ballot with 61 names during Tuesday's primary to replace outgoing Democratic Gov. Gavin Newsom. The race has no clear front-runner and includes a mix of Democrats and Republicans. The primary operates under a "jungle" system, meaning the top two finishers, regardless of party, will advance to the general election. Key contenders include Democrat Xavier Becerra, a former U.S. House member and Biden cabinet member, and billionaire Tom Steyer, known for his climate change advocacy. Republican Steve Hilton, endorsed by Trump, is emphasizing lower taxes and smaller government.

The war in Iran threatens to disrupt international travel to Asia, where the tourism industry has yet to fully recover from the the COVID‑19 pandemic. Airspace closures, the rerouting of flights around the Middle East and elevated jet fuel costs are driving up airfares, causing flight cancelations and lengthening travel times on key routes between Europe and Thailand, Cambodia, Vietnam and other destinations. A recent report by the United Nations Development Program says higher airfares and weaker travel confidence can quickly affect livelihoods and public revenues in economies where visitor arrivals are a major source of jobs, income and foreign currency.

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Businesses big and small have started receiving refunds after the U.S. Supreme Court ruled that President Donald Trump improperly imposed some tariffs on imported goods. But the Trump administration said on Friday that it would appeal a federal judge’s order making all companies that paid the duties eligible for refunds, not just the ones that filed lawsuits. U.S. Customs and Border Protection says the first refunds reached the bank accounts of successful applicants on May 12 and that it had accepted applications worth $85 billion for processing as of last week. The amount is about half of the $166 billion that CBP estimated the government owed more than 330,000 companies that paid the invalidated tariffs.

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Artificial intelligence is helping a London-based singer-songwriter continue writing and recording music after Parkinson’s disease largely took away his ability to play guitar. Samuel Smith relied on AI-powered song generators to create the demos for one track on his new album, “The Art of Letting Go.” He says the apps allowed him to convey his vision to the session musicians who recorded the song after his guitar skills deteriorated. AI music generators like Suno and and Udio use models trained on large datasets of recorded music and audio. The technology has divided the music industry and produced copyright infringement lawsuits. Smith gets it. He also thinks his experience demonstrates AI's potential to expand creative access.

Russian intelligence agencies have grown more aggressive in their efforts to steal Western technology and defense secrets as sanctions squeeze the country’s wartime economy. That's according to three senior European intelligence officials who spoke to The Associated Press. They say Moscow’s agents are building fake companies, recruiting middlemen and deploying cyber spies and hackers who are gathering information that could also be used to attack key infrastructure. Four years of international sanctions have hampered Moscow’s ability to procure machinery, technology and research from Europe. The grinding war in Ukraine has meanwhile taxed key industries and pushed Russia toward a possible financial crisis.