The winning $42.5 million Hoosier Lotto jackpot ticket was purchased at On the Fly #822 store at 1448 12th Street in Tell City, Indiana.
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The Hoosier Lottery released the location where the ticket was sold.
He had five numbers that matched the March 25th drawing to win $225,000.
The jackpot is the third-largest in U.S history after 31 straight drawings without a winner.
If someone hits the jackpot, the cash option is an estimated $370.5 million.
Wednesday's estimated jackpot, $550 million, is the eighth-largest in Powerball history.