DraftKings has noticed, installing Louisville as a 7.5-point favorite to finish the season with the Cards' 11th victory.
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This one is a different. This one is a chance to make more than a statement. This one is a chance to make a memory.
For 37 years, the Indiana football program has been able to say it won its last meeting against the Louisville Cardinals.
It's Monday, and time for a reset look at Louisville, Kentucky, Indiana and Western Kentucky.
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As expected, Cardinal fans are considerably more gaga about new coach Jeff Brohm, his staff and the rebuilt roster than they were about the outgoing regime.