Musa Msafiri, 57, is charged with assault and DUI.
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The crash happened just before 2 a.m. on Bluegrass Avenue, according to a news release from Louisville Metro Police Department Spokeswoman Alicia Smiley.
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Police say the motorcyclist rear ended a car, was thrown into traffic and then hit by another vehicle that didn't stop.
The fire at an apartment complex on Bluegrass Avenue near Southern Parkway was reported about 8:30 p.m.