LOUISVILLE, Ky. (WDRB) -- Hundreds of murderers are still on the loose, and Louisville Metro Police are determined to put every single one behind bars.  Detectives are working more than 450 cold cases murders. 

"We're still hoping and praying that something will come up," said Sandra Cheatham, mother of a Louisville murder victim.

Eight years of hoping and praying is a long time.  That's how long Sandra Cheatham has been waiting for closure in her son's murder.

"And I think that was the worst day of my life," she said.

In May 2005, Tyrone Cheatham was stabbed to death outside an apartment on Sebree Lane in the Norfolk neighborhood.  His family still doesn't know who did it, why or even how.

"It could have been scissors, it could have been a knife, but it was a small point and it was just right...right in here," said Cheatham, pointing to the center of her neck.

Cheathem's case is one of 459 cold case murders being investigated by Louisville Metro Police.

"An eight year old case, those leads have drawn up.  I mean, nobody is calling in leads anymore, unless we get it out there that, 'Hey, we're looking for leads on certain cases," said Sgt. Donny Burbrink III, with LMPD Cold Case Homicides and Missing Persons.

"The tips are very important," Sgt. Burbrink said.

He also says with the right tip, any case can be solved -- even the ones dating back decades.

"Sometimes it's just that one small tip that will break open a case," said Sgt. Burbrink.

"And I've heard where they've had cases that's 20 years old that has been solved," said Cheatham.

And that's why Sandra Cheathem still has confidence something will happen with her son's case. 

"I still believe that it will be solved one day, whether it's in our time or not."

Police say tips have helped solve dozens of cases over the years.  Anyone with information on the Cheatham case or any other murder can call the anonymous police tip line at 574-LMPD.

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