McConnell, the longest-serving Senate party leader in U.S. history, revealed in February, on his 83rd birthday, that he won't seek another term.
He attended Greater Louisville Inc.'s Capitol Connection series, which gives local business leaders the chance to hear from elected officials.
McConnell spoke on a variety of topics ranging from inflation, the upcoming presidential election and the United States' position as a world leader.
The move will end his history-setting tenure as the Senate's longest serving party leader.
McConnell was at dinner on March 8 after a hotel reception for a campaign committee aligned with him when he tripped and fell.
The Kentucky senator, 81, was at a dinner for the Senate Leadership Fund, when he tripped Wednesday evening.
Kentucky U.S. Sen. Mitch McConnell made history Tuesday as the longest serving party leader in either party in the U.S. Senate in American history.
McConnell also mentioned how FEMA could have done more to help flooding recovery efforts in eastern Kentucky.
The Louisville Muhammad Ali International Airport will soon get a $400 million renovation, and U.S. Sen. Mitch McConnell came to town Tuesday to lobby for federal money to fund the work.
He's the longest serving Senate Republication leader in American history.