Indiana regulators voted Monday to eliminate the reformulated gasoline requirement in Clark and Floyd counties, a change officials said could lower gas prices for local drivers.
While some Kentucky drivers will continue receiving a 10-cent break on the state's gas tax, many others will lose the savings because their local officials did not request the extension.
The program had been in place since the 1990s as part of an effort to reduce air pollution in the region.
With prices increasing from 30 cents to 60 cents more from one day to the next, some say they don't know if they'll be able to afford another spike.
The average price across the country is $4.14, meaning most gas stations in the Louisville area are above the national average.
The requirement has led Louisville drivers to pay as much as 35 cents more per gallon than surrounding counties and other parts of the state.
Mayor Craig Greenberg said on Wednesday that work over the past several decades has helped improve air quality and meet EPA requirements to get rid of RFG.
The price of gas in Louisville could drop if the city is allowed to switch from reformulated gas to conventional gas.
Mayor Craig Greenberg said Louisville is now in a spot where the city could go back to using conventional gas because the city's air quality has improved.
Some stations in Louisville are charging nearly $4.40 per gallon.