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The third generation owner blames changes to how pharmacies are reimbursed for prescriptions by insurance companies.
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Several WDRB News viewers in Kentucky and Indiana say their experience at pharmacies has become more difficult lately while trying to get prescriptions.
Appointments for people 65 and older can be made on the stores' websites.
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As part of a new federal pharmacy program, Kentucky is also opening 125 federal pharmacy sites across the site, which will be split up between 78 Walgreens and 47 independent pharmacies.
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The chain is also offering flu shots at its pharmacies and Little Clinics.