Humana Building downtown 500 W Main Street 9-12-22 (2).JPG
The Humana Tower at 500 W. Main Street in downtown Louisville, Sept. 12, 2022.Â
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Humana, the only Fortune 500 company headquartered in Kentucky, plans to vacate its headquarters building at 500 W. Main Street to "centralize" its Louisville employment in the company’s Waterside-Clocktower campus on the east side of downtown.
