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Good Brothers Pharmacy is the brain child of Isaiah Jones and Deshawn King, who have deep roots in the west end.
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Many see the closing as the loss of a vital west end resource.
Louisville will still have 20 CVS locations, but for anyone in the west end, downtown will now be the closest option, roughly a 3-mile walk.
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The third generation owner blames changes to how pharmacies are reimbursed for prescriptions by insurance companies.
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Police referred to Howard as Grainger's "former romantic partner," but Grainger said that's not true. She said they were only co-workers who went to lunch one time.
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25-year-old Anthony Howard was arrested early Wednesday morning.
The company said it will not dispense the drug mifepristone, the first of two drugs in the medication abortion process, by mail.
Walmart pharmacies also will start closing at 7 p.m. at about 4,600 stores beginning in March.
The commonwealth will receive more than $197 million combined from both pharmacy chains.
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The products were sold nationwide at major stores including Rite Aid, CVS, Walmart, Target and Amazon