The family is hoping to get more than 100 donors.
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The new location replaces the old one that was located at 12905 Shelbyville Road, which closed on Oct. 26.
This year, organizers are hoping to reach 400 units of donated blood.
The 17th annual Be the Match registry was held Sunday at Holy Family Church on Poplar Level Road.
Seth recently celebrated one year in remission.
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The organization's holiday blood drive will run from 11 a.m. to 7 p.m. on Dec. 26 and 27 in Ballrooms A and B of the Crowne Plaza Hotel.