No serious injuries were reported, according to police.

The ramp is currently shut down and crews are on site working the scene.

The interstate was shut down for about six hours after the crash around 7:30 a.m. Monday.

The cocaine found has a street value worth of $400,000. 

LMPD's Traffic Unit is investigating.

Louisville Metro Police spokeswoman Alicia Smiley said a car headed east on Interstate 264 lost control near the Shelbyville Road exit and drove under the rear axle of a semi-truck.

The Clark County Sheriff's Department said the semi driver saw the train coming in the distance at Highway 31 North and Riley Drive.

In 2014, the National Transportation Safety Board, the federal agency that investigates crashes, recommended that all new large trailers have side protection systems.