According to ISP, officers tried to stop the fleeing driver multiple times before he came to a stop on an off-ramp on I-65.
At this time, all southbound lanes of Interstate 65 are closed while crews clean up the diesel fuel spill from the trucks' saddle tanks.
The 55th annual Street Rod Nationals is being held at the Kentucky Exposition Center through Sunday.
LMPD's Traffic Unit is investigating.
According to ISP, the armed male entered the bank, pointed a gun at employees, and then fled on foot with cash.
KSP received a report at 1:12 p.m. Monday that Elizabeth Ann Edwards, of Bedford, hasn't been seen since midnight.
ISP said a trooper stopped a white Hyundai passenger car in Jeffersonville for speeding and an equipment violation near Spring Street and Court Avenue.
The Seymour Police Department posted on social media that the crash happened about 10:46 p.m. on Friday on South Vine Street.
When the two vehicles reached the crest of the hill, they crashed head-on.
ISP said troopers responded to a single-vehicle crash on County Road 1000 East near County Road 250 North, just miles south of Seymour.