Wainwright will perform a large selection of songs from his "Want One" and "Want Two" albums.
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Tickets go on sale this Friday, April 7, at 10 a.m.
The weekend will spotlight local musicians, eateries and non-profits.
Country Music Hall of Famer Ronnie Milsap will be joining the group for the Louisville show
The free concerts, hosted by 91.9 WFPK, open at 5 p.m. with music beginning at 6 p.m.
The four-time Grammy Award winner had his March 2020 performance at the KFC Yum! Center canceled by the COVID-19 pandemic and rescheduled twice.